Evaluation of Anti Inflammatory Activity of Phyllanthus Longiflorus in Experimental Animal Models

نویسنده

  • M. JESUPILLAI
چکیده

Anti inflammatory potential of aerial parts of Phyllanthus longiflorus was investigated in the present study using acute and chronic inflammatory models. Carrageenan, dextran and formalin were used as an edematogenic agent to induce hind paw edema in rats and the mean increase in paw volume were measured using plethysmometer. Results showed that methanol extract of Phyllanthus longiflorus at the doses of 100 and 200 mg/kg body weight significantly reduced in hind paw edema induced by Carrageenan, dextran and formalin. Therefore, it is concluded that Phyllanthus longiflorus is useful in the management of inflammatory diseases.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of Anti-Arthritic and Anti-Inflammatory Activity of Sudard, a Poly Herbal Formulation

Rheumatoid arthritis is a chronic multi-system disease of unknown cause. It affects the people in their prime of life, predominantly between the ages of 20-50 years with unpredictable course. Sudard is used in the ayurvedic system of medicine for the treatment of inflammation and pain associated with rheumatoid arthritis, osteo-arthritis, frozen shoulder, sciatica, ankylosing spondylitis and ...

متن کامل

Evaluation of anti convulsant activity of aerial parts of Phyllanthus longiflorus heyne ex hook.

OBJECTIVE To evaluate anti convulsant effect of aerial parts of Phyllanthus longiflorus (PHL). MATERIALS AND METHOD Methanol extract of aerial parts of PHL (MPHL) was prepared by continuous hot extraction method using Soxhlet apparatus. MPHL at the doses 100, 200 and 400 mg/kg were administered to male albino mice by oral route and the activity was assessed against maximal electro shock (MES)...

متن کامل

Evaluation of Anti-inflammatory Activity of Methanolic Extract of Solanum nigrum (Solanaceae)

      The methanolic extract of whole plants of Solanum nigrum L. was investigated for anti-inflammatory activity on the experimental animal models. The methanolic extract at a concentration of 100 mg.kg-1 and 200 mg.kg-1, p.o. showed the significant dose dependent anti-inflammatory activity in carrageenin and egg white induced hind paw oedema in rats. An...

متن کامل

Evaluation of Anti-inflammatory and Analgesic Activity of the Extract and Fractions of Astragalus hamosus in Animal Models

Aim of the study: The objective of this study was to evaluate the anti-inflammatory and analgesic activities of the hydro-alcoholic extract of the pods of Astragalus hamosus (HAAH), a plant used in Iranian traditional medicine, and antinociceptive effects of different fractions in animal models. Material and methods: The anti-inflammatory effect was evaluated by the rat paw edema induced by for...

متن کامل

Evaluation of Anti-inflammatory and Analgesic Activity of the Extract and Fractions of Astragalus hamosus in Animal Models

Aim of the study: The objective of this study was to evaluate the anti-inflammatory and analgesic activities of the hydro-alcoholic extract of the pods of Astragalus hamosus (HAAH), a plant used in Iranian traditional medicine, and antinociceptive effects of different fractions in animal models. Material and methods: The anti-inflammatory effect was evaluated by the rat paw edema induced by for...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014